What about the cavitation of Ultrasonic liquid processor in the fields of killing virus such as COVID-19?
Ultrasonic Liquid Processor| Homogenizer is widely used in the fields of biology, microbiology, physics, zoology, agronomy, pharmacy, petroleum, etc. Also suitable for sample preparation in the chemical, medical, archaeological, address, marine and other fields. It also can be used in Nanotechnology research such as the dispersion of nanomaterials (nanotubes, graphene, silica, etc.); emulsification, homogenization and fragmentation of nano-materials such as carbon nanotubes, graphene and other materials, homogeneous soil, rock samples, non-ferrous metals, rare earths and other particles.Lysis, disruption, leaching, extraction of DNA, protein extraction from animal and plant cells, pruning DNA/RNA, chromatin immunoprecipitation technology for cells, viruses, spores and other cell structures.
What about the cavitation of Ultrasonic liquid processor in the fields of killing virus such as COVID-19?
Let's see the two function of the ultrasonic processor/homogenizer:
The first is the cavitation of ultrasound.
Ultrasound can produce a large number of high-pressure and high-temperature bubbles, which can burst and release a large amount of heat. As long as a certain period of time, it can destroy the cell wall of bacteria
The second function is the resonance effect of ultrasound, which has no sterilization effect.
Now If according to the normal conditions of splitting cells, ultrasonic processor can't kill the virus, but in this process, due to the high temperature, bubbles and so on, the virus will be damaged, and the virus will naturally die after a long time, but the damage of ultrasound itself to the virus is not big.
When we do experiment of making virus antigen, it is necessary to add virus inactivator into buffer used for ultrasonic cracking. At the same time, take the buffer without inactivator as the control. After ultrasonic cracking, the lysate without inactivator and the lysate with inactivator are inoculated with cells to isolate virus at the same time. As a result, the lysate without inactivator can separate virus, and the lysate with inactivator can not separate virus, so it can meet the product acceptance standard.
