How does an ultrasonic processor work?

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Introduction

Basic Operation of Ultrasonic Electronic Generator
The ultrasonic electronic generator converts AC line power to a 20 KHz signal that powers a piezoelectric convertor/transducer. The transducer in turn converts this electrical signal to a mechanical vibration because of the attributes of the internal piezoelectric crystals.This mechanical vibration is intensified and passed down the length of the probe or horn where the tip expands and contracts longitudinally. The distance travelled by the tip depends on the amplitude chosen by the user via the amplitude control knob.

Cavitation


In liquid, the fast vibration of the tip results in the formation and collapse of microscopic bubbles. This phenomenon is dubbed as cavitation. The breakdown of countless number of cavitation bubbles, releases significant amount of energy in the cavitation field.Following this, surfaces and objects inside the cavitation field are processed. The diameter of the probe tip controls the amount of sample that can be suitably processed. Diameters of smaller tips i.e. microtip probes provide high intensity sonication; however the energy is directed inside a small, concentrated area. Although larger volumes are processed by larger tip diameters, they deliver low intensity sonication.

Conclusion


The options of a generator and horns or probes correspond to several factors, such as viscosity, volume, etc. of a specific application. A Misonix Sonicator product specialist can help in choosing the right generator and horn for particular applications.

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Cell Disruption

Nanoparticle Dispersion

Creating Emulsions

Shearing DNA

ChIP Assay

Homogenization